SB 216763

Product Code: GFC0666

Catalog Number	Unit Size	Price
GFC0666-1 mg	1 mg	Online Inquiry
GFC0666-10 mg	10 mg	Online Inquiry
GFC0666-50 mg	50 mg	Online Inquiry

Description

Potent, selective GSK-3 inhibitor. Equally effective at inhibiting human GSK-3α and GSK-3β. Exhibits minimal activity against 24 other protein kinases. Stimulates glycogen synthesis in liver cells, and induces β-catenin-dependent gene transcription. Shown to maintain mouse embryonic stem cells in a pluripotent state.

Specification

Chemical Name

3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Formula

C19H12Cl2N2O2

Molecular Weight

371.22

Purity

≥98% (HPLC)

CAS No.

280744-09-4

PubChem

176158

InChi Key

JCSGFHVFHSKIJH-UHFFFAOYSA-N

SMILES String

CN1C=C(C2=CC=CC=C12)C1=C(C(=O)NC1=O)C1=C(Cl)C=C(Cl)C=C1

Storage

Store at Room Temperature. Store under desiccating conditions.

For research or further manufacturing use only. Not for use in humans.