Cytokines

Human RSPO1

Product Code: GFC0145

Description

R-Spondin 1 (RSPO1) is the prototype member of the R-Spondin (RSPO) protein subfamily of a superfamily of thrombospondin type 1 repeat (TSR-1)-containing proteins. RSPO1 is involved in a wide range of pleiotropic roles during embryogenesis, it is required for the specification of hematopoietic stem cells, and it has been shown to be important in the growth, survival, and migration of ovarian cancer cells.

Specification

Source

CHO

Symbols

hRspo1, Roof plate-specific Spondin-1, CRISTIN3, RSPO

Accession

Q2MKA7

AA Sequence

RISAEGSQACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSRRRKGQQQQQQQGTVGPLTSAGPA

Molecular Mass

25.6 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by luciferase activity induced in HEK-293 cells in the presence of mouse Wnt-3a is ≥ 2.0 x 10^4 units/mg (EC50 ≤ 50 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.