Cytokines

Human OSM, animal component-free

Product Code: GFC0137

Description

Oncostatin-M (OSM) is a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family. OSM is involved in differentiation, cell proliferation, hematopoiesis, and inflammation, and also has been shown to have implications in liver development, bone formation and resorption.

Specification

Source

E. coli

Symbols

OSM, Oncostatin M

Accession

P13725

AA Sequence

MAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYIRIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKAQDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTPASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRR

Molecular Mass

23.8 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using TF-1 cells is ≥ 2.5 x 10^5 units/mg (EC50 ≤ 4 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.