Cytokines

Human NTF3

Product Code: GFC0134

Description

Neurotrophin 3 (NTF3) is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. NTF3 is known to promote survival, development, and differentiation of neurons, and modulates transmitter release at several types of synapses in the peripheral and central nervous systems. NTF3 has been shown to have an important role in the overall development of enteric neurons, which are crucial for gut peristalsis.

Specification

Source

E. coli

Symbols

HGNF, NGF-2, Nerve growth factor 2, Neurotrophin 3, NT3, NGF2, NT-3

Accession

P20783

AA Sequence

MYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT

Molecular Mass

27.5 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using C6 cells is ≥ 50 units/mg (EC50 ≤ 20 μg/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.