Cytokines

Human LEP

Product Code: GFC0121

Description

Leptin (LEP) is a protein that is secreted by white adipocytes into the circulation and acts as both a hormone involved in metabolic function as well as a proinflammatory cytokine by inducing Th1 immune responses. LEP can both promote osteogenesis via osteoblast receptors and inhibit it through its actions on the hypothalamus.

Specification

Source

E. coli

Symbols

FLJ94114; LEP; LEPD protein; leptin (murine obesity homolog); leptin (obesity homolog, mouse); OB; Obese protein; Obese, mouse, homolog of; Obesity factor; OBOBS

Accession

NP_000221.1

AA Sequence

MVPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC

Molecular Mass

16 kDa

Purity

≥ 95%

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.