Cytokines

Human IL-3

Product Code: GFC0097

Description

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including mast cells, basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes.

Specification

Source

CHO

Symbols

Hematopoietic growth factor, Interleukin-3, Mast cell growth factor, MCGF, MGC79398, MGC79399, Multi-CSF, Multilineage-colony-stimulating factor, Multiple colony-stimulating factor, Multipotential colony-stimulating factor, P-cell-stimulating factor

Accession

Q6GS87

AA Sequence

APMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF

Molecular Mass

15.1 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using TF-1 cells is ≥ 1.0 x 10^7 units/mg (EC50 ≤ 0.1 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.