Cytokines

Mouse IL-3

Product Code: GFC0096

Description

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including mast cells, basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes.

Specification

Source

E. coli

Symbols

HCGF, Interleukin-3, MCGF, Multi-CSF, P-cell stimulation factor

Accession

P01586

AA Sequence

MDTHRLTRTLNCSSIVKEIIGKLPEPELKTDDEGPSLRNKSFRRVNLSKFVESQGEVDPEDRYVIKSNLQKLNCCLPTSANDSALPGVFIRDLDDFRKKLRFYMVHLNDLETVLTSRPPQPASGSVSPNRGTVEC

Molecular Mass

15.2 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using NFS-60 cells is ≥ 4 x 10^6 units/mg (EC50 ≤ 0.25 ng/mL) .

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.