Cytokines

Mouse IL-1 alpha

Product Code: GFC0086

Description

Interleukin 1 alpha (IL-1 alpha) is a member of the IL-1 family and a dual-function cytokine. IL-1 alpha recruits infiltrating cells to a site of injury during necrosis and plays an important role during processes of sterile inflammation. During hypoxia, IL-1 alpha contributes to angiogenesis.

Specification

Source

E. coli

Symbols

BAF, B-cell-activating factor, Epidermal cell-derived thymocyte-activating factor, ETAF, FAF, Fibroblast-activating factor, IL-1F1, LAF, LEM, Leukocyte endogenous mediator, Lymphocyte-activating factor, MCF, Mononuclear cell factor

Accession

P01582

AA Sequence

MSAPYTYQSDLRYKLMKLVRQKFVMNDSLNQTIYQDVDKHYLSTTWLNDLQQEVKFDMYAYSSGGDDSKYPVTLKISDSQLFVSAQGEDQPVLLKELPETPKLITGSETDLIFFWKSINSKNYFTSAAYPELFIATKEQSRVHLARGLPSMTDFQIS

Molecular Mass

18.1 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using D10.G4.1 cells is ≥ 1.0 x 10^8 units/mg (EC50 ≤ 0.01 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.