Cytokines

Human IHH

Product Code: GFC0071

Description

Indian hedgehog (IHH) is one of three proteins in the hedgehog family which includes sonic hedgehog and desert hedgehog. IHH is strongly expressed in cartilage and regions of developing bone, and its signaling regulates growth and differentiation of bone tissue. It is also involved in yolk sac vasculogenesis, indicating a role in the differentiation of epiblast cells into endothelial and red blood cells.

Specification

Source

E. coli

Symbols

BDA1, HHG2, Indian hedgehog protein

Accession

Q14623

AA Sequence

CGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAAAKTGG

Molecular Mass

19.7 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by an alkaline phosphatase assay using CCL-226 cells is ≥ 3.3 x 10^2 units/mg (EC50 ≤ 3 μg/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.