Mouse IGF1

Product Code: GFC0069

Description

Insulin-like growth factor 1 (IGFI) is a polypeptide which belongs to the family of insulin-like growth factors that are similar in molecular structure to proinsulin. IGFI binds to the IGFI receptor and is a potent activator of the PI3K/AKT pathway; it also activates ERK1/2 signaling. IGFI is required for embryonic development, and it is produced mainly in liver in response to a hepatocyte growth hormone.

Specification

Source
E. coli
Symbols
IBP1, IGF-IA, IGF-IB, IGF1A, Mechano growth factor, MGF, Somatomedin C
Accession
P05017
AA Sequence
MGPETLCGAELVDALQFVCGPRGFYFNKPTGYGSSIRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPTKAA
Molecular Mass
7.8 kDa
Purity
≥ 95%
Bioactivity
The specific activity as determined by a cell proliferation assay using FDC-P1 cells is ≥ 1 x 10^5 units/mg (EC50 ≤ 10 ng/mL).
Storage
Store at -80°C. Avoid repeated freeze-thaw cycles.
For research or further manufacturing use only. Not for use in humans.

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