Cytokines

Human IFNA2

Product Code: GFC0062

Description

Interferon alpha 2 (IFNA2) is a type I interferon, produced by virus-infected cells, and is released as a soluble factor to initiate antiviral responses. Type I IFNs exert potent antitumor activity by increasing the cytotoxic activity of NK and T cells, as well as by inhibiting the proliferation of cancer cells.

Specification

Source

E. coli

Symbols

IFN-alpha 2,IFN-alpha-2, IFN-alphaA, IFNAB, leIF A, IFNA2

Accession

P01563

AA Sequence

MCDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE

Molecular Mass

19.4 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a viral challenge assay using encephalomyocarditis (EMC) virus on A549 cells is ≥ 2 x 10^8 units/mg (EC50 ≤ 5 pg/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.