Cytokines

Human FGF8

Product Code: GFC0049

Description

Fibroblast growth factor 8 (FGF8) is a member of the fibroblast growth factor (FGF) family. The FGF family possesses broad mitogenic and cell survival activities and is involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis. FGF8 is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells.

Specification

Source

E. coli

Symbols

AIGF, AIGFKAL6, Androgen-induced growth factor, FGF-8, Fibroblast growth factor 8 (androgen-induced), Fibroblast growth factor 8, HBGF-8, Heparin-binding growth factor 8, MGC149376

Accession

P55075

AA Sequence

MQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR

Molecular Mass

21.3 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using 3T3 cells in the presence of 1 μg/mL heparin is ≥ 2 × 10^3 units/mg (EC50 ≤ 500 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.