Cytokines

Human CXCL2

Product Code: GFC0033

Description

CXCL12 is a member of stromal cell-derived alpha chemokine family. It functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis.

Specification

Source

E. coli

Symbols

CXCL2, GRO2, Growth regulated protein, Melanoma growth stimulatory activity, MGSAβ, MIP-2α, CINC-2a, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2

Accession

P19875

AA Sequence

APLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN

Molecular Mass

7.9 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a Ca2+ mobilization assay using CHO-K1/Gα15/hCXCR2 cells is ≥ 5.0 x 10^3 units/mg (EC50 ≤ 0.2 μg/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.