Cytokines

GMP Human TNF

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Product Code: G-GFC0099

Description

GMP Human TNF (P01375), is expressed in E.coli under cGMP guidelines.

Specification

Source

E.coli

Symbols

Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor , DIF, Necrosin, Cytotoxin

Accession

P01375

AA Sequence

MVRSSSRTPS DKPVAHVVAN PQAEGQLQWL NRRANALLAN GVELRDNQLV VPSEGLYLIY SQVLFKGQGC PSTHVLLTHT ISRIAVSYQT KVNLLSAIKS PCQRETPEGA EAKPWYEPIY LGGVFQLEKG DRLSAEINRP DYLDFAESGQ VYFGIIAL

Molecular Mass

Approximately 17.5 kDa.

Purity

≥95% by SDS-PAGE and HPLC analyses.

Bioactivity

The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 IU/mg in the presence of actinomycin D.

Storage

Store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.