Cytokines

GMP Human IL-1 alpha

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Product Code: G-GFC0053

Description

GMP Human IL-1 alpha (P01583) is produced in E.coli under cGMP guidelines.

Specification

Source

E.coli

Symbols

Lymphocyte-activating factor, LAF, Leukocyte Endogenous Mediator, LEM, Endogenous Pyrogen, EP, Mononuclear Cell Factor, MCF, Hematopoietin-1

Accession

P01583

AA Sequence

SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA

Molecular Mass

Approximately 18.0 kDa.

Purity

≥95% by SDS-PAGE and HPLC analyses.

Bioactivity

The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg/ml, corresponding to a specific activity of > 1.0 × 109 IU/mg.

Storage

Store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.