Cytokines

GMP Human BDNF

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Product Code: G-GFC0002

Description

GMP Human BDNF is produced in Sf 21 under cGMP guidelines. It contains AA His129-Arg247 (Accession # NP_001137277).

Specification

Source

insect cell

Symbols

BDNF; brain-derived neurotrophic factor; neurotrophin; abrineurin; MGC34632;

Accession

NP_001137277

Molecular Mass

The predicted molecular mass is 13.5 kDa
SDS-PAGE: 13-14 kDa, reducing conditions

Purity

≥95%

Bioactivity

The ED50 as determined by a cell proliferation assay using BaF mouse pro-B cells transfected with TrkB is 0.2-2 ng/ml.
The specific activity of recombinant human/mouse/rat BDNF is approximately 1.3 x 10^3 units/μg, which is calibrated against recombinant human BDNF WHO Standard (NIBSC code: 96/534).

Storage

Store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.