Product Code: CB0540
Catalog Number | Unit Size | Price |
---|---|---|
CB0540-1 mg | 1 mg | Online Inquiry |
CB0540-10 mg | 10 mg | Online Inquiry |
CB0540-50 mg | 50 mg | Online Inquiry |
CB0540-100 mg | 100 mg | Online Inquiry |
Description
TG101348 is an inhibitor of Janus kinase 2 with an IC₅₀ of 6 nM. It also inhibits related kinases fms-related tyrosine kinase 3 , RET, and JAK3 with less potent activity, having IC₅₀ values of 25, 17 and 169 nM, respectively . It is proposed to bind to the ATP binding pocket of its kinase targets.
Specification