Product Code: CB0519
Catalog Number | Unit Size | Price |
---|---|---|
CB0519-1 mg | 1 mg | Online Inquiry |
CB0519-10 mg | 10 mg | Online Inquiry |
CB0519-50 mg | 50 mg | Online Inquiry |
CB0519-100 mg | 100 mg | Online Inquiry |
Description
Refametinib is an inhibitor of both mitogen-activated protein kinase kinases 1 and 2 with IC₅₀ values of 19 and 47 nM respectively. It binds in an allosteric site adjacent to the ATP pocket and is selective for MEK1/2 versus 205 other kinases .
Specification