JAK Inhibitor I

Product Code: CB0486

Catalog Number	Unit Size	Price
CB0486-1 mg	1 mg	Online Inquiry
CB0486-10 mg	10 mg	Online Inquiry
CB0486-50 mg	50 mg	Online Inquiry
CB0486-100 mg	100 mg	Online Inquiry

Description

Janus Associated Kinase Inhibitor I is a pyridine-containing tetracycle that disrupts JAK activity by interacting with the ATP binding domain. This inhibitor inhibits mouse JAK3 with Ki = 5 nM, JAK family members TYK2 and JAK2 with IC50 = 1 nM, and mouse JAK1 with IC50 = 15 nM, while showing weaker inhibition of other kinases.

Specification

Sterility Testing

Non-Sterile

Form

Powder

Species

Human, Mouse, Rat, Non-Human Primate, Other

Cell Type

Pluripotent Stem Cells

Shipping Condition

Dry Ice

Limitations

Research Use Only

For research or further manufacturing use only. Not for use in humans.