IQ-1

Product Code: CB0480

Catalog Number	Unit Size	Price
CB0480-1 mg	1 mg	Online Inquiry
CB0480-10 mg	10 mg	Online Inquiry
CB0480-50 mg	50 mg	Online Inquiry
CB0480-100 mg	100 mg	Online Inquiry

Description

IQ-1 selectively inhibits p300-dependent β-catenin signaling by binding to the PR72/130 subunit of protein phosphatase PP2A, leading to decreased phosphorylation of the β-catenin coactivator, p300, and decreased affinity of p300 for β-catenin. IQ-1 thereby inhibits β-catenin/p300 interaction while increasing β-catenin/CBP mediated transcription.

Specification

Sterility Testing

Non-Sterile

Form

Powder

Species

Human, Mouse, Rat, Non-Human Primate, Other

Cell Type

Cancer Cells and Cell Lines, Cardiomyocytes, PSC-Derived, Pluripotent Stem Cells

Shipping Condition

Dry Ice

Limitations

Research Use Only

For research or further manufacturing use only. Not for use in humans.