Product Code: CB0462
Catalog Number | Unit Size | Price |
---|---|---|
CB0462-1 mg | 1 mg | Online Inquiry |
CB0462-10 mg | 10 mg | Online Inquiry |
CB0462-50 mg | 50 mg | Online Inquiry |
CB0462-100 mg | 100 mg | Online Inquiry |
Description
GSA 10 is an agonist of Smoothened , a cell surface receptor and mediator of the hedgehog signaling pathway. It is a quinolinecarboxamide derivative that binds in a distinct binding pocket from cyclopamine. GSA10 is active at an EC₅₀ of 1.2 μM in an alkaline phosphatase-based mouse mesenchymal cell line differentiation assay.
Specification