Fumonisin B1

Product Code: CB0457

Catalog Number	Unit Size	Price
CB0457-1 mg	1 mg	Online Inquiry
CB0457-10 mg	10 mg	Online Inquiry
CB0457-50 mg	50 mg	Online Inquiry
CB0457-100 mg	100 mg	Online Inquiry

Description

Fumonisin B1 is a mycotoxin produced by Fusarium moniliforme that has been shown to potently inhibit sphingosine N-acyltransferase , thereby disrupting the synthesis of sphingolipids, a key component of plasma membranes . Fumonisin B1 also inhibits protein serine/threonine phosphatases with IC₅₀ values of 80 - 3000 μM. PP5 is the most sensitive with an IC₅₀ of 80 μM . Fumonisin B1, together with Alfatoxin B1, increases reactive oxygen species levels and oxidative damage in rat spleen cells.

Specification

Sterility Testing

Non-Sterile

Form

Powder

Species

Human, Mouse, Rat, Non-Human Primate, Other

Cell Type

Cancer Cells and Cell Lines, Keratinocytes, Leukemia/Lymphoma Cells, Neurons

Shipping Condition

Dry Ice

Limitations

Research Use Only

For research or further manufacturing use only. Not for use in humans.