Dasatinib

Product Code: CB0438

Catalog Number	Unit Size	Price
CB0438-1 mg	1 mg	Online Inquiry
CB0438-10 mg	10 mg	Online Inquiry
CB0438-50 mg	50 mg	Online Inquiry
CB0438-100 mg	100 mg	Online Inquiry

Description

Dasatinib is a potent, ATP-competitive tyrosine kinase inhibitor. It is specific for SRC/ABL kinases, for example, ABL, SRC, LCK, and YES with IC₅₀ values of < 1.0, 0.5, 0.4 and 0.5 nM, respectively, and also demonstrates activity against KIT with an IC₅₀ = 5.0 nM Dasatinib is a second-generation inhibitor of the oncogenic tyrosine kinase BCR-ABL with 325-fold more potency than imatinib, and is also able to inhibit imatinib-resistant BCR-ABL mutants .

Specification

Sterility Testing

Non-Sterile

Form

Powder

Species

Human, Mouse, Rat, Non-Human Primate, Other

Cell Type

Cancer Cells and Cell Lines, Leukemia/Lymphoma Cells

Shipping Condition

Dry Ice

Limitations

Research Use Only

For research or further manufacturing use only. Not for use in humans.