Penicillin-Streptomycin-Neomycin Solution contains ~5,000 units Penicillin, 5 mg Streptomycin and 10 mg Neomycin/mL. This solution is used to control bacterial contamination as a supplement of cell culture media.
Penicilin, derived from Penicillium fungi, can interfere with the bacterial cell-wall synthesis.
Streptomycin, produced by Streptomyces, can inhibit prokaryote protein synthesis by binding to the bacterial ribosome and inhibit complex of protein synthesis.
Neomycin can inhibit initiation and elongation during protein synthesis of bacteria.
