Human NRG1-beta1/HRG1-beta1 EGF Domain Antibody, Unconjugated

Product Code: CB2428

Catalog Number	Unit Size	Price
CB2428-25 ug	25 ug	Online Inquiry
CB2428-100 ug	100 ug	Online Inquiry
CB2428-500 ug	500 ug	Online Inquiry

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Clone Number

147705

Label

Unconjugated

Source

E. coli-derived recombinant human NRG1-beta1/HRG1-beta1, Ser2-Lys246, Accession # AAA58639

Specificity

Detects human NRG1-beta 1 in ELISAs. Recognizes an epitope found in the EGF-like domain of NRG1-beta 1 (amino acids 179-246). It also detects recombinant human SMDF (Sensory and Motor neuron-Derived Factor), but it does not recognize the EGF-like domain of human NRG1-alpha (amino acids 177-241). The epitope is present within amino acids 213-230 of human NRG1-beta 1. This segment is present in all NRG1 beta isoforms, GGF-2 (glial growth factor), and SMDF, but it is absent from NRG1-alpha, NDF43, and NRG1-gamma.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

ELISA

Alternate Names

ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; neuregulin 1; Neuregulin1 beta 1; Neuregulin-1 beta 1; NRG1-IT2; SMDF

Entrez Gene IDs/Gene IDs

3084 (Human); 211323 (Mouse); 112400 (Rat)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.