Human Neuregulin-1/NRG1 Antibody, Unconjugated

Product Code: CB1435

Catalog Number	Unit Size	Price
CB1435-25 ug	25 ug	Online Inquiry
CB1435-100 ug	100 ug	Online Inquiry
CB1435-500 ug	500 ug	Online Inquiry

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Clone Number

147724

Label

Unconjugated

Source

E. coli-derived recombinant human Neuregulin-1/NRG1, Ser2-Lys246, Accession # AAA58639

Specificity

Detects human Neuregulin-1/NRG1 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with the EGF-like domains of recombinant human (rh) NRG1-beta 1 (aa 176-246) or rhNRG1-alpha (aa 177-241). Therefore, this antibody recognizes an epitope located within aa 2-176 segment N-terminal to the EGF-like domain. This segment is present in all NRG1-alpha, beta and gamma isoforms and in NDF43 and glial growth factor (GGF). It is absent from the NRG1 gene products GGF2 and SMDF.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Western Blot

Alternative Names

ARIA; GGF2; GGFglial growth factor; Heregulin-1; HGL; HGLneu differentiation factor; HRG; HRG1; HRG1-alpha; HRG1-beta 1; HRGAneuregulin 1 type IV beta 1a; MST131; MSTP131; NDFheregulin, alpha (45kD, ERBB2 p185-activator); neuregulin 1 type IV beta 3; neuregulin 1; Neuregulin1; Neuregulin-1; NRG1; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; SMDF

Entrez Gene IDs/Gene IDs

3084 (Human); 211323 (Mouse); 112400 (Rat)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.6 months, -20 to -70 °C under sterile conditions after reconstitution.

For research or further manufacturing use only. Not for use in humans.