Human VISTA/B7-H5/PD-1H Antibody, APC-conjugated

Product Code: CB0931

Catalog Number	Unit Size	Price
CB0931-100 Tests	100 Tests	Online Inquiry

Description

VISTA (V-domain Ig suppressor of T cell activation), also known as platelet receptor Gi24, is a member of the Ig superfamily and is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. Gi24 interacts with BMP-4 to enhance BMP signaling and the transition from an undifferentiated to a differentiated state; and promotes the expression and activity of MT1-MMP and serves as a substrate for MT1-MMP.

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Clone Number

730804

Label

Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Source

Mouse myeloma cell line NS0-derived recombinant human VISTA/B7-H5/PD-1H, Phe33-Ala194, Accession # Q9H7M9

Specificity

Detects human VISTA/B7-H5/PD-1H in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse VISTA/B7-H5/PD-1H is observed.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Application

Flow Cytometry

Alternative Names

4632428N05Rik; B7H5; B7-H5; C10orf54; chromosome 10 open reading frame 54; Dies1; Gi24; PD1H; PD-1H; platelet receptor Gi24; PP2135; SISP1; stress induced secreted protein 1; VISTA; VSIR

Entrez Gene IDs/Gene IDs

64115 (Human); 74048 (Mouse); 690899 (Rat); 102116468 (Cynomolgus Monkey)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At 2 - 8°C for one year. Protect from light.

For research or further manufacturing use only. Not for use in humans.