Human VISTA/B7-H5/PD-1H Antibody, Unconjugated

Product Code: CB0929

Catalog Number	Unit Size	Price
CB0929-25 ug	25 ug	Online Inquiry
CB0929-100 ug	100 ug	Online Inquiry

Description

VISTA (V-domain Ig suppressor of T cell activation), also known as platelet receptor Gi24, is a member of the Ig superfamily and is a transmembrane molecule expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. Gi24 interacts with BMP-4 to enhance BMP signaling and the transition from an undifferentiated to a differentiated state; and promotes the expression and activity of MT1-MMP and serves as a substrate for MT1-MMP.

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Clone Number

1011484

Label

Unconjugated

Source

Mouse myeloma cell line NS0-derived recombinant human VISTA/B7-H5/PD-1H, Phe33-Ala194, Accession # Q9H7M9

Specificity

Detects human VISTA/B7-H5/PD-1H in direct ELISAs.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Flow Cytometry; Blockade of Receptor-ligand Interaction; CyTOF-ready

Alternative Names

4632428N05Rik; B7H5; B7-H5; C10orf54; chromosome 10 open reading frame 54; Dies1; Gi24; PD1H; PD-1H; platelet receptor Gi24; PP2135; SISP1; stress induced secreted protein 1; VISTA; VSIR

Entrez Gene IDs/Gene IDs

64115 (Human); 74048 (Mouse); 690899 (Rat); 102116468 (Cynomolgus Monkey)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.