Human TROP-2 Antibody, PE-conjugated

Product Code: CB0923

Catalog Number	Unit Size	Price
CB0923-100 Tests	100 Tests	Online Inquiry

Description

TROP2 (Trophoblast cell surface antigen 2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis.

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Clone Number

77220

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Source

Mouse myeloma cell line NS0-derived recombinant human TROP-2, His27-Thr274, Accession # P09758

Specificity

Detects human TROP-2 in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) VCAM-1 or rhICAM-1 is observed.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Application

Flow Cytometry

Full Name

Tumor-associated Calcium Signal Transducer 2

Alternative Names

Cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733-1; GA733-1GP50; gastrointestinal tumor-associated antigen GA7331; gp50; M1S1cell surface glycoprotein TROP2; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733; T16; TACSTD2; TROP2; TROP-2; TROP2GA7331; tumor-associated calcium signal transducer 2

Entrez Gene IDs/Gene IDs

4070 (Human); 56753 (Mouse)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At 2 - 8°C for one year. Protect from light.

For research or further manufacturing use only. Not for use in humans.