Human TROP-2 Antibody, Unconjugated

Product Code: CB0920

Catalog Number	Unit Size	Price
CB0920-25 ug	25 ug	Online Inquiry
CB0920-100 ug	100 ug	Online Inquiry
CB0920-500 ug	500 ug	Online Inquiry

Description

TROP2 (Trophoblast cell surface antigen 2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis.

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Clone Number

77220

Label

Unconjugated

Source

Mouse myeloma cell line NS0-derived recombinant human TROP-2, His27-Thr274, Accession # P09758

Specificity

Detects human TROP-2 in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) VCAM-1 or rhICAM-1 is observed.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Western Blot; Flow Cytometry; CyTOF-ready

Full Name

Tumor-associated Calcium Signal Transducer 2

Alternative Names

Cell surface glycoprotein Trop-2; EGP1; EGP-1; epithelial glycoprotein-1; GA733-1; GA733-1GP50; gastrointestinal tumor-associated antigen GA7331; gp50; M1S1cell surface glycoprotein TROP2; Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733; T16; TACSTD2; TROP2; TROP-2; TROP2GA7331; tumor-associated calcium signal transducer 2

Entrez Gene IDs/Gene IDs

4070 (Human); 56753 (Mouse)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.