Human Oct-4A Antibody, Unconjugated

Product Code: CB0896

Catalog Number Unit Size Price
CB0896-25 ug 25 ug Online Inquiry
CB0896-100 ug 100 ug Online Inquiry

Description

OCT-4 (octamer-binding transcription factor 4), also known as POU5F1, is a homeodomain transcription factor of the human POU family. This protein plays a key role in the self-renewal of undifferentiated embryonic stem cells. The expression of OCT-4 is potentially correlated with tumorigenesis and can affect some aspects of tumor behavior, such as tumor recurrence or resistance to therapies. OCT-4 is expressed in undifferentiated pluriopotency cells, germ cells in ovary and testes. OCT-4 is a sensitive and specific marker for germ cell tumors.

Specification

Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Clone Number
653108
Label
Unconjugated
Source
E.coli-derived recombinant human Oct-4A, Met1-Glu135, Accession # NP_002692
Specificity
Detects human Oct-4A in Western Blots.
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Application
Western Blot; CyTOF-ready; Immunocytochemistry; Flow Cytometry
Full Name
Octamer-binding Transcription Factor 4A
Alternative Names
OCT3;Oct-3;OCT4;Oct-4;OCT4;Oct3/4;OTF3;OTF-3;OTF4;POU domain protein;POU domain, class 5, transcription factor 1;POU5F1; Oct4A; Oct-4A
Entrez Gene IDs/Gene IDs
5460 (Human); 18999 (Mouse)
Endotoxin
<0.10 EU/μg by the LAL method.
Storage
At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
For research or further manufacturing use only. Not for use in humans.

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