Human LIN-28A Antibody, Unconjugated

Product Code: CB0874

Catalog Number	Unit Size	Price
CB0874-25 ug	25 ug	Online Inquiry
CB0874-100 ug	100 ug	Online Inquiry

Description

LIN28 is one of the four key human factors (OCT4, SOX2, NANOG and LIN28) used to reprogram human fibroblasts to an embryonic stem (ES) cell-like state known as the induced pluripotent stem (Ips) cell. Lin28 is a marker of undifferentiated human embryonic stem cells and a cytoplasmic Mrna-binding protein that binds to and enhances the translation of the IGF2 Mrna. LIN28 has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells. Affinity purified rabbit anti-LIN28 can be used to demonstrate pluripotency of ES and Ips cells, and to detect LIN28 transgene expression in the process of reprogramming.、

Specification

Reactivity

Human

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Label

Unconjugated

Source

E. coli-derived recombinant human LIN-28A, Met1-Asn209, Accession # Q9H9Z2

Specificity

Detects human LIN-28A in direct ELISAs and Western Blots.

Purification

Antigen Affinity-purified

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Western Blot; Immunocytochemistry

Full Name

RNA-binding Protein LIN-28

Alternative Names

CSDD1; CSDD1lin-28A; FLJ12457; lin-28 homolog (C. elegans); lin-28 homolog A (C. elegans); LIN28; LIN-28; LIN28A; LIN-28A; LIN28RNA-binding protein LIN-28; Tex17; ZCCHC1; ZCCHC1protein lin-28 homolog A; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1

Entrez Gene IDs/Gene IDs

79727 (Human); 83557 (Mouse); 298542 (Rat)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.