Human Integrin alpha 6/CD49f Antibody, Unconjugated

Product Code: CB0867

Catalog Number	Unit Size	Price
CB0867-25 ug	25 ug	Online Inquiry
CB0867-100 ug	100 ug	Online Inquiry

Description

Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrin alpha 6 (also VLA-6, CD49F and ITA6) is a 130‑150 kDa member of the integrin alpha chain family of molecules. Mature Integrin alpha 6 is a 1107 amino acid (aa) type I transmembrane glycoprotein that contains a 1027 aa extracellular region and a 93 aa cytoplasmic tail. Integrin alpha 6 forms a non-disulfide-linked heterodimeric complex with both integrin beta 1 and beta 4. Each complex serves as a receptor for laminin.

Specification

Reactivity

Human

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Label

Unconjugated

Source

E. coli-derived recombinant human Integrin alpha 6/CD49f, Pro93-Arg148, Ile557-Arg613, Accession # P23229

Specificity

Detects human Integrin alpha 6/CD49f in direct ELISAs and Western Blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Integrin alpha 9 is observed and less than 1% cross-reactivity with rhIntegrin alpha 2, recombinant mouse (rm) Integrin alpha 3, rhIntegrin alpha 7, and rmIntegrin alpha 7 is observed.

Purification

Antigen Affinity-purified

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Western Blot; Simple Western

Alternative Names

CD49 antigen-like family member F; CD49f antigen; CD49f; DKFZp686J01244; FLJ18737; Integrin alpha 6; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; Platelet gpl; VLA-6

Entrez Gene IDs/Gene IDs

3655 (Human); 16403 (Mouse); 101925271 (Cynomolgus Monkey)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.