Human/Mouse/Bovine Integrin alpha 6/CD49f Antibody

Product Code: CB0863

Catalog Number	Unit Size	Price
CB0863-25 ug	25 ug	Online Inquiry
CB0863-100 ug	100 ug	Online Inquiry

Description

Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrin alpha 6 (also VLA-6, CD49F and ITA6) is a 130‑150 kDa member of the integrin alpha chain family of molecules. Mature Integrin alpha 6 is a 1107 amino acid (aa) type I transmembrane glycoprotein that contains a 1027 aa extracellular region and a 93 aa cytoplasmic tail. Integrin alpha 6 forms a non-disulfide-linked heterodimeric complex with both integrin beta 1 and beta 4. Each complex serves as a receptor for laminin.

Specification

Reactivity

Human, Mouse, Bovine

Clonality

Monoclonal

Host

Isotype

IgG2A

Clone Number

Source

Mouse mammary tumor cells

Specificity

Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit.

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Flow Cytometry; Immunohistochemistry; Blockade of Receptor-ligand Interaction; CyTOF-ready

Alternative Names

CD49 antigen-like family member F; CD49f antigen; CD49f; DKFZp686J01244; FLJ18737; Integrin alpha 6; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; Platelet gpl; VLA-6

Entrez Gene IDs/Gene IDs

3655 (Human); 16403 (Mouse); 101925271 (Cynomolgus Monkey)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.

USA

Europe

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