Human Alkaline Phosphatase/ALPL Antibody, Unconjugated

Product Code: CB0813

Catalog Number Unit Size Price
CB0813-25 ug 25 ug Online Inquiry
CB0813-100 ug 100 ug Online Inquiry

Description

Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. As the name suggests, alkaline phosphatase is most effective in an alkaline environment.
Alkaline phosphatases (APs) are ubiquitous in many species from bacteria to human. Four genes encode AP isoenzymes in humans and rodents. Three AP genes are expressed in a tissue-specific manner (i.e., placental, embryonic, and intestinal AP isoenzymes). Expression of the fourth AP gene is nonspecific to a single tissue and is particularly abundant in bone, liver, and kidney. This isoenzyme is also known as tissue-nonspecific alkaline phosphatase (TNAP).

Specification

Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Clone Number
928929
Label
Unconjugated
Source
Mouse myeloma cell line NS0-derived recombinant human Alkaline Phosphatase/ALPL, Leu18-Ser502, Accession # P05186
Specificity
Detects human Alkaline Phosphatase/ALPL in direct ELISA and Western Blots.
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Application
Western Blot; Immunohistochemistry
Full Name
Alkaline Phosphatase Liver
Alternative Names
Akp2; Alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase, liver/bone/kidney; alkaline phosphatase, tissue-nonspecific isozyme; alkaline phosphomonoesterase; ALPL; APTNAP; AP-TNAP; EC 3.1.3.1; FLJ40094; FLJ93059; glycerophosphatase; HOPS; liver/bone/kidney-type alkaline phosphatase; MGC161443; tissue-nonspecific ALP; TNAP; TNSALP; TNSALPMGC167935
Entrez Gene IDs/Gene IDs
249 (Human); 11647 (Mouse)
Endotoxin
<0.10 EU/μg by the LAL method.
Storage
At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
For research or further manufacturing use only. Not for use in humans.

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