Human Activin RIIB Antibody

Product Code: CB0809

Catalog Number	Unit Size	Price
CB0809-25 ug	25 ug	Online Inquiry
CB0809-100 ug	100 ug	Online Inquiry

Description

Members of the TGF-β superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activin receptor type IIB is a type II receptor that mediates multiple signals from TGF‑β family members, including Activin, Nodal, Bmp7, Gdf1, Gdf3, Myostatin (Gdf8), and Gdf11.

Specification

Reactivity

Human

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Clone Number

60402

Source

Mouse myeloma cell line NS0-derived recombinant human Activin RIIB, Ser19-Thr134, Accession # Q13705

Specificity

Detects human Activin RIIB in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, approximately 5% cross-reactivity with recombinant human Activin RIIA is observed.

Purification

Protein A or G purified from ascites

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Application

Western Blot

Full Name

Activin Receptor IIB

Alternative Names

activin A receptor, type IIB; Activin receptor type IIB; activin receptor type-2B; Activin RIIB; ActivinRIIB; ACTRIIB; ActR-IIB; ACVR2B; EC 2.7.11; EC 2.7.11.30; MGC116908

Entrez Gene IDs/Gene IDs

93 (Human); 11481 (Mouse)

Endotoxin

<0.10 EU/μg by the LAL method.

Storage

At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

For research or further manufacturing use only. Not for use in humans.