Human Activin RIIA/B Antibody

Product Code: CB0807

Catalog Number Unit Size Price
CB0807-25 ug 25 ug Online Inquiry
CB0807-500 ug 500 ug Online Inquiry

Description

Members of the TGF-β superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activin receptor type IIB is a type II receptor that mediates multiple signals from TGF‑β family members, including Activin, Nodal, Bmp7, Gdf1, Gdf3, Myostatin (Gdf8), and Gdf11.

Specification

Reactivity
Human
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Clone Number
60401
Source
Mouse myeloma cell line NS0-derived recombinant human Activin RIIB, Ser19-Thr134, Accession # Q13705
Specificity
Detects human Activin RII in direct ELISA and Western Blots.
Purification
Protein A or G purified from ascites
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Small pack size is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Application
Western Blot
Full Name
Activin Receptor IIA/B
Alternative Names
Activin RIIA/B; ACTRII; ACVR2
Endotoxin
<0.10 EU/μg by the LAL method.
Storage
At -20°C for one year. After reconstitution , at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
For research or further manufacturing use only. Not for use in humans.

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