Napabucasin

Product Code: GFC0668

Catalog Number	Unit Size	Price
GFC0668-10 mg	10 mg	Online Inquiry
GFC0668-50 mg	50 mg	Online Inquiry

Description

STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model.

Specification

Chemical Name

2-Acetylnaphtho[2,3-b]furan-4,9-dione

Formula

C14H8O4

Molecular Weight

240.21

Purity

≥98% (HPLC)

CAS No.

83280-65-3

PubChem

10331844

InChi Key

DPHUWDIXHNQOSY-UHFFFAOYSA-N

SMILES String

O=C(C1=C2C=C(C(C)=O)O1)C3=CC=CC=C3C2=O

Storage

Store at -20°C. Store under desiccating conditions.

For research or further manufacturing use only. Not for use in humans.

USA

Europe

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