Recombinant Human FGF-3 Protein

Product Code: GFC0589

Catalog Number	Unit Size	Price
GFC0589-25 ug	25 ug	Online Inquiry

Description

Fibroblast Growth Factor 3 (FGF-3) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

Specification

Source

E. coli-derived human FGF-3 protein, Asp28-Arg212, with an N-terminal Met

Reactivity

Human

N-terminal Sequence

Met

Purity

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Molecular Mass (Predicted)

21.1 kDa

Accession

NP_005238

Biological Activity

Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. Rizzino, A. et al. (1988) Cancer Res. 48:4266; Thomas, K. et al. (1987) Methods Enzymol. 147:120. The ED50 for this effect is 0.02-0.1 µg/mL in the presence of 1 µg/mL of heparin.

Endotoxin

<0.10 EU per 1 μg of the protein by the LAL method.

Application

Bioactivity

For research or further manufacturing use only. Not for use in humans.