Recombinant Human TGF-beta 1 Protein, Sf9-derived

Product Code: GFC0571

Catalog Number	Unit Size	Price
GFC0571-10 ug	10 ug	Online Inquiry
GFC0571-25 ug	25 ug	Online Inquiry

Description

Transforming growth factor beta 1 (TGF-β1) is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. Recombinant human TGF-β1 is used for the cultivation of embryonic stem cells and induced pluripotent stem cells, but can also promote Th17 and Treg differentiation of T cells.

Specification

Source

Spodoptera frugiperda, Sf9 (baculovirus)-derived human TGF-beta 1 protein, Ala279-Ser390
Produced in an animal component free process (ACFP).

Reactivity

Human

N-terminal Sequence

Ala279

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Molecular Mass (Predicted)

12.8 kDa (monomer)

SDS-PAGE

11 kDa, reducing conditions

Accession

P01137

Biological Activity

Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389. The ED50 for this effect is 0.0400-0.200 ng/mL.

Endotoxin

<0.10 EU per 1 μg of the protein by the LAL method.

Application

Bioactivity

For research or further manufacturing use only. Not for use in humans.