Recombinant Human BMP-4 Protein, GMP grade

Product Code: G-GFC0560

Catalog Number	Unit Size	Price
G-GFC0560-50 ug	50 ug	Online Inquiry

Description

Bone Morphogenetic Protein 4 (BMP-4) is a polypeptide belonging to the TGFβ protein superfamily and plays pivotal roles in bone and cartilage formation, tissue repair, or organ and neuronal development. Recombinant human BMP-4 can ideally be used for functional assays, cell culture, and differentiation studies.

Specification

Source

E. coli-derived human BMP-4 protein, Lys303-Arg408
Produced in an animal-free laboratory. Manufactured and tested under cGMP guidelines.

Reactivity

Human

N-terminal Sequence

Identity was confirmed by mass spectrometry

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Molecular Mass (Predicted)

12 kDa

SDS-PAGE

8-9 kDa, reducing conditions

Accession

P12644.1

Biological Activity

Measured by its ability to induce BMP responsive SEAP reporter activity in HEK293 human embryonic kidney cells. The ED50 for this effect is 3-21 ng/mL.

Endotoxin

<0.10 EU per 1 μg of the protein by the LAL method.

Application

Bioactivity

For research or further manufacturing use only. Not for use in humans.