Recombinant Human BMP-4 Protein, E. coli-derived

Product Code: GFC0560

Catalog Number	Unit Size	Price
GFC0560-10 ug	10 ug	Online Inquiry
GFC0560-50 ug	50 ug	Online Inquiry

Description

Bone Morphogenetic Protein 4 (BMP-4) is a polypeptide belonging to the TGFβ protein superfamily and plays pivotal roles in bone and cartilage formation, tissue repair, or organ and neuronal development. Recombinant human BMP-4 can ideally be used for functional assays, cell culture, and differentiation studies.

Specification

Source

E. coli-derived human BMP-4 protein, Lys303-Arg408

Reactivity

Human

N-terminal Sequence

Lys303

Purity

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.

Molecular Mass (Predicted)

12 kDa

SDS-PAGE

8-9 kDa, under reducing conditions

Accession

P12644.1

Biological Activity

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is 6-48 ng/mL.

Endotoxin

<0.10 EU per 1 μg of the protein by the LAL method.

Application

Bioactivity

For research or further manufacturing use only. Not for use in humans.