Human IL-2 IS, research grade

E. coli

Human

Human IL-2 IS can be used for a variety of applications including:

In vitro activation and propagation of T cells, e.g., in combination with the T Cell Activation/Expansion Kit, human.
In vitro stimulation of cytolytic function and expansion of NK cells, e.g., using the NK Cell Activation/Expansion Kit, human.
Generation of lymphokine-activated killer (LAK) cells or cytokine-induced killer (CIK) cells.

3×10^6 IU/mg

IL-2, a potent lymphoid cell growth factor, is a typical four α-helix bundle cytokine. It is produced by activated T cells, especially the CD4+ T helper cell population. It plays an important role in both the activation and maintenance of immune responses and in lymphocyte development. IL-2 promotes proliferation and differentiation of T cells, NK cells and B cells and is involved in the elimination of self-reactive T cells. IL-2 signals through a receptor complex consisting of IL-2 receptor α-chain (CD25), β- chain, and common γ-chain. The latter two are also used for IL-15 signaling.