Recombinant Human IL-15

Product Code: GFC0549

Catalog Number	Unit Size	Price
GFC0549-2µg	2µg	Online Inquiry
GFC0549-10µg	10µg	Online Inquiry
GFC0549-50µg	50µg	Online Inquiry
GFC0549-100µg	100µg	Online Inquiry
GFC0549-250µg	250µg	Online Inquiry
GFC0549-500µg	500µg	Online Inquiry
GFC0549-1mg	1mg	Online Inquiry

Description

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant Human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.

Specification

Sample Resource

E.coli

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Synonyms

Interleukin-15, IL-T

AA Sequence

MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS

Biological Activity

The ED50 as determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells was found to be ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

Calculated Molecular Weight

12.9 kDa

Accession Number

P40933

Gene ID

3600

For research or further manufacturing use only. Not for use in humans.