Product Code: GFC0538
| Catalog Number | Unit Size | Price |
|---|---|---|
| GFC0538-2µg | 2µg | Online Inquiry |
| GFC0538-10µg | 10µg | Online Inquiry |
| GFC0538-50µg | 50µg | Online Inquiry |
| GFC0538-100µg | 100µg | Online Inquiry |
| GFC0538-250µg | 250µg | Online Inquiry |
| GFC0538-500µg | 500µg | Online Inquiry |
| GFC0538-1mg | 1mg | Online Inquiry |
Description
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant Human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues.
Specification
