Recombinant Human IL-16 (121 a.a.)

Product Code: GFC0548

Catalog Number	Unit Size	Price
GFC0548-2µg	2µg	Online Inquiry
GFC0548-10µg	10µg	Online Inquiry
GFC0548-50µg	50µg	Online Inquiry
GFC0548-100µg	100µg	Online Inquiry
GFC0548-250µg	250µg	Online Inquiry
GFC0548-500µg	500µg	Online Inquiry
GFC0548-1mg	1mg	Online Inquiry

Description

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells, CD4+ monocytes, and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant Human IL-16 is a 12.4 kDa protein consisting of 121 amino acid residues.

Specification

Sample Resource

E.coli

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Synonyms

LCF (Lymphocyte Chemoattractant Factor)

AA Sequence

SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S

Biological Activity

Determined by its ability to chemoattract human CD4+ T lymphocytes using a concentration range of 50.0-100.0 ng/ml.

Calculated Molecular Weight

12.4 kDa

Accession Number

Q14005

Gene ID

For research or further manufacturing use only. Not for use in humans.

USA

Europe

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