Animal-Free Recombinant Human GM-CSF

Product Code: GFC0531

Catalog Number	Unit Size	Price
GFC0531-5µg	5µg	Online Inquiry
GFC0531-20µg	20µg	Online Inquiry
GFC0531-50µg	50µg	Online Inquiry
GFC0531-100µg	100µg	Online Inquiry
GFC0531-250µg	250µg	Online Inquiry
GFC0531-500µg	500µg	Online Inquiry
GFC0531-1mg	1mg	Online Inquiry

Description

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

Specification

Sample Resource

E.coli

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Synonyms

Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α

AA Sequence

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

Biological Activity

The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Calculated Molecular Weight

14.6 kDa

Accession Number

P04141

Gene ID

1437

Endotoxin

Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

For research or further manufacturing use only. Not for use in humans.