SuperEXP® Human CD1c (BDCA-1)+ Dendritic Cell Isolation Kit

Product Code: RS1185

Description

The SuperEXP® Human CD1c (BDCA-1)+ Dendritic Cell Isolation Kit has been developed for the isolation of CD1c (BDCA-1)+ myeloid dendritic cells (MDCs; type-1 MDC or cDC2) from PBMCs. This new format allows for the optional depletion of CD14+ myeloid cells that recently have been shown to possibly contaminate the final DC population.

Specification

Species

Human

Application

CD1c (BDCA-1)+ dendritic cells can be used for a variety of applications, for example:

Isolation of CD1c (BDCA-1)+ myeloid dendritic cells to examine expression of Toll-like receptors, chemokine receptors, or new antigens, e.g., DCAL-1 and EMR2.
Isolation for studies on dendritic cell activation, migration, cytokine production and T cell polarization, particularly in comparison with monocyte-derived dendritic cells.
Isolation of CD1c+ DCs for studies evaluating new checkpoint inhibitors or dissecting their mechanisms of actions in tumor settings.

For research or further manufacturing use only. Not for use in humans.