Cytokines

Mouse IL-7, His tag

Product Code: GFC0114

Description

Interleukin 7 (IL-7) is a member of the Type I cytokine family that is critical for T and B cell development and survival. IL-7 regulates the survival of naïve and memory CD4+ and CD8+ T cells, γδ T cells, NK T cells, innate lymphoid cells, and T regulatory cells. Although a deficiency in IL-7R still permits the generation of normal numbers of peripheral B cells in humans, stimulation of human B cell precursors with IL-7 could promote STAT-5-dependent proliferation and survival in vitro.

Specification

Source

CHO

Tag

His

Symbols

Interleukin-7, LP-1, Lymphopoietin 1, Pre-B cell factor

Accession

Q544C8

AA Sequence

ECHIKDKEGKAYESVLMISIDELDKMTGTDSNCPNNEPNFFRKHVCDDTKEAAFLNRAARKLKQFLKMNISEEFNVHLLTVSQGTQTLVNCTSKEEKNVKEQKKNDACFLKRLLREIKTCWNKILKGSIHHHHHH

Molecular Mass

15 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using 2E8 cells is ≥ 2.5 x 10^6 units/mg (EC50 ≤ 0.4 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.