Cytokines

Mouse IL-6

Product Code: GFC0108

Description

Interleukin 6 (IL-6) is a pleiotropic growth factor with a wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis. On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells. In combination with cytokines such as IL-3, GM-CSF, and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro.

Specification

Source

E. coli

Symbols

B cell differentiation factor, BSF-2, IFN-β2, Interleukin-6

Accession

P08505

AA Sequence

MFPTSQVRRGDFTEDTTPNRPVYTTSQVGGLITHVLWEIVEMRKELCNGNSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLLEYHSYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPISNALLTDKLESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQT

Molecular Mass

21.9 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using 7TD1 cells is ≥ 1 x 10^6 units/mg (EC50 ≤ 1 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.